Lexeo Therapeutics

LEXEO Therapeutics is a clinical-stage gene therapy company developing treatments for rare genetic conditions. They aim to become a gene therapy leader for cardiac diseases.

Lexeo was referred to us by Longitude Capital in 2021, during their preparation for Series B financing. They needed practical guidance to distill clear messaging and build a compelling corporate story for upcoming investor meetings.

We followed our typical process, which involved diving deep into their scientific concepts, reviewing their materials, and conducting interviews with their executive team. From there, we crafted a comprehensive strategy, including clear positioning and messaging, coupled with simple graphics and scientific illustrations to create a persuasive investor presentation and corporate website.

Our strategy highlighted LEXEO’s programs and business objectives, leading to a successful Series B round raising $100M.

We’ve been working with Lexeo ever since, and one of their latest requests was to help them create a patient recruitment site that explains gene therapy in a clear, illustrative way. We’ve created a website using illustrations and simple language to help them connect with patients.

Responsive website design for Lexeo Therapeutics, emphasizing support for individuals living with genetic diseases with the tagline 'Your Strength, Your Bravery, and Fortitude.' A lighthouse illustration symbolizes guidance.
This slide, part of Lexeo Therapeutics' educational content on their patient website, explains gene therapies by first discussing cells in the human body, including the nucleus and chromosomes. Illustrations of a cell, nucleus, and chromosome are included.
A slide, from Lexeo Therapeutics' investor deck, outlining the reasons for choosing AAVrh.10 as their gene therapy delivery platform, citing efficient CNS transduction, greatest cardiac affinity, lower pre-existing immunity, and their clinical experience.
This slide from Lexeo Therapeutics' investor deck illustrates their strategy, highlighting programs in cardiac (Friedreich's Ataxia) and CNS (CLN2 Batten, APOE4 Alzheimer's) using intravenous and CNS administration of their AAVrh.10 platform.
An illustrative slide explaining the disease mechanism of CLN2 Batten and how Lexeo Therapeutics' LX1004, an AAV-mediated transfer of TPP1 gene, aims to treat it by restoring TPP1 expression in lysosomes.
Responsive website design for Lexeo Therapeutics with the tagline 'Breaking New Ground in Genetic Medicine,' emphasizing gene therapy for devastating diseases. An abstract, possibly DNA-related, visual is in the background.
This shows Lexeo Therapeutics' website focusing on their cardiac programs, specifically LX2006 for Cardiac Friedreich's Ataxia, providing a list of programs and details about this condition.