July 28, 2020

ALX Oncology case study

This close-up illustration depicts the basal state interaction between a macrophage and a cancer cell. The cancer cell expresses CD47, which binds to SIRPα on the macrophage, sending a 'don't eat me' signal and inhibiting phagocytosis.2 This illustrates the checkpoint that ALX Oncology aims to block.

There is no surprise that life sciences field is very competitive, some areas more than others. It is a great challenge for up and coming life science companies to differentiate […]